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Tiny trailblazer

Kumudini Hettiarachchi meets the first all-Lankan test tube baby, her proud parents and grand parents and the team of doctors who created this miracle

Click image for a larger view
Click image for a larger view

She kept us up till 3.30 a.m.," says the new mother as I peer into the cradle at a red-faced baby, swathed in pink. Kept warm by two small pillows with bright blue covers with balloons printed all over them, the tiny baby girl opens her eyelids a fraction and quickly closes them as if to shut out the world.

Though a miracle as the birth of a baby is, it's nothing special - another baby and mother, with a concerned grandmother hovering around in a room at Durdans Hospital. Wrong. This tiny face hasn't launched a thousand ships like the famous Helen of Troy, but has been on the front pages of all the newspapers and even been beamed across the world. A test tube baby, yes, a test tube baby but "conceived", looked after and brought into the world by caesarian section under the care of a wholly local team. That's a first, for all the test tube babies born in Sri Lanka earlier had a foreign touch in their making.

On Tuesday, July 2, when I visit them, all is quiet in the room where three generations can be seen - grandmother, mother and baby. The baby is in her cradle and the mother has more or less recovered from the operation.

"I've longed for this moment since the day I got married eight years ago. My dream has come true," says the mother.

After being married for a while, the fretting began when there was no sign of a baby to complete their joy. Their relatives and friends also wondered and worried. "We've not had a childless couple in our families," says the grandmother.

The mental agony increased. Living in the outstations, the couple consulted a doctor who sent them to Colombo and then on to the Vindana Reproductive Health Centre, where an able team took over.

A battery of tests later, both for the husband and wife, the in-vitro fertilization (IVF) technology was explained to them. They tried it out and the pregnancy began in September 2001.

What is IVF? It is giving a "helping hand to nature" for the ovum to get fertilized by a sperm, outside the body of the mother, according to the Vindana team, comprising Prof. Harsha Seneviratne, Dr. Athula Kaluarachchi, Dr. (Mrs.) Champa Nelson and embryologist Mrs. Sumedha Wijeratne.

Explaining the procedure, the team says, "Eggs are taken out of the mother's body in the operating theatre, cleansed of blood and other tissue, put in a nutritious culture medium and placed in an incubator to develop. Sperm is also extracted from the father."

"An egg each is introduced to sperm droplets in a petri dish and once again placed in an incubator and kept for about 18 hours to fertilize. The fertilized egg, now a microscopic baby or embryo, with a distinct identity with two nuclei is allowed to grow in a culture medium which is changed frequently to give it all the nutrition it needs and in about three days implanted in the uterus," adds Embryologist Wijeratne, who looked after the creation of the baby girl.

From then on it takes the course of a normal pregnancy. And all this talk of fertilization occurring in a "test tube" is simply not true. The fusion, in fact takes place in a petri dish.

"Don't wait until the mother is very old. The moment you realize there is a problem, go to a doctor, for the mother's age is of paramount importance. If all tests reveal that there is simply no other way you can have a child, then get it done before the mother grows too old. Before the mother becomes 35 would be good," says Dr. Nelson, adding, "The younger the better."

"We are so proud to be part of this pioneering effort where only Sri Lankan expertise brought forth this baby," says the grandmother her eyes moist with emotion, for this is her very first grandchild.

"Yes, we are sad that the baby's father is unavoidably out of the country on work at this joyous time, but there is a lot of happiness that we are making history."

They will take the 3.15 kilo baby born at 5.31 on the morning of July 1 to the Kelaniya Vihare to fulfil a vow they made to see a happy ending to their childless ordeal.

And through all the excitement and joy, what does this tiny trailblazer think? A big yawn is the only response I get.

Don't blame the woman
A "barren" marriage as most of us call childless couples could be due to many reasons. In the past, society pointed an accusing finger at the woman, blaming her for not having a child, but in recent times such attitudes have changed with both partners being tested for either infertility or sub-fertility.

Statistics are hard to find, but male infertility can be attributed to 30-50% of cases of childlessness among infertile couples, says well-known Urologist Dr. Lalith Perera.

"There are several reasons, but environmental pollution and chemicals in what we eat seem to be major contributory factors for male infertility. Hormones are being added to the meats we eat. In other countries it has been found that estrogen (the female hormone) is given to chickens to make them grow quickly," says Prof. Harsha Seneviratne.


Reasons for infertility

Female factors

  • Failure of ovulation due to a hormonal imbalance
  • Blocked or damaged fallopian tubes
  • Endometriosis which is caused by the womb lining starting to grow in other places in the reproductive system and sometimes even elsewhere
  • Fibroids
  • Hostile cervical mucus

Male factors

  • Failure of sperm production
  • Blocked/absent vas deferens (tubes connecting the testes to the exterior)
  • Low sperm numbers
  • Poor sperm movement
  • High numbers of abnormal forms
  • Anti-sperm antibodies

There are also patients with unexplained infertility where all the investigations performed on the couple are normal, but who still do not conceive with routine treatments.

Taking that important decision to try out IVF
When a couple decides to try out IVF to have that much-longed for baby, experts remind that there are many factors they should look into.

A childess couple has to accept that there is a problem and that usually is a very difficult thing to do. Once they concede that, they need counselling to come to terms with it. Then of course, comes the next step of finding out the cause for being childless and accepting that it may not be treatable, but working within it to try and overcome the problem. In many cases, why a couple cannot conceive remains a mystery forever.

Counselling and clearing up doubts are an essential part of this process and with a success rate of around 30% the patients need to have a clear picture that though they agree to the procedure, the end result may be negative.

Next comes the need for total commitment and practically putting every other thing in their lives on hold. The injections and the ultra-sound scans have to be done on time, to give a few examples of the time and effort required.

Another important area for most infertile couples would be finding the money to meet the cost of a minimum of Rs. 300,000 for a basic procedure, but which could be more depending on the individual woman's requirements.

Once such a treatment is decided on, comes the question of ethics. The patients' personal feelings on such an issue and the need to maintain the privacy and confidentiality of those trying out such a procedure.

Interwoven into all this is the confidentiality factor not only on the part of the doctors and others looking after the patients, but also the patients themselves and society's attitude towards them. "A change in society's attitude is essential. A child born through the assisted reproductive technique (ART) should not be a curiosity. ART should be looked at as another mode of treatment for infertility," urges Prof. Harsha Seneviratne, senior gynaecologist and obstetrician.

What of the government's role?

"The government needs to get involved in bringing about a rational policy on such reproductive technologies, so that it regulates and acts as a guiding body," stresses Prof. Seneviratne.

Sri Lanka could in fact take a leaf out of the Indian book, where there has been state involvement in the process from the very beginning. When the technology was being tried out in the west, the Indian government had set apart funding for research within the country and the first test tube baby had been born to a streetsweeper.

If infertility is on the rise, another area in which the Sri Lankan government could get involved, in addition to setting out policy would be to help the common man and woman find the funding in the form of loans etc. to meet their yearning for a baby.


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